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KMID : 0378019710140020088
New Medical Journal
1971 Volume.14 No. 2 p.88 ~ p.90
Effect of Korean Ginseng and Cortisone on the Serum Glucose, Insulin and Free Fatty Acids of Rabbits received Oral Glucose-Loading


Abstract
This work was carried out in order to study whether Korean Ginseng (Panax C. A. Mey) could compete hyperglycemia.
Three groups of healthy rabbits weighing about 1. 5kg were fed same food as the first control group, but the second group was given 1.Ogm of ginseng mixed with food, and the third group was given ginseng-mixed and injected 0. 25mg of cortisone everyday for 10 days. Serum glucose, free fatty acids, insulin, potassium and sodium were checked after 8 hour¢¥s fasting. And all the animals were fed 1.0gm/ (kg body weight) of glucose orally. Then serum glucose was checked at 30, 60 and 120 minutes after oral glucose-loading.
From my serum chemistry and some other author¢¥s reports, the possible role of ginseng competing hyperglycemia or the action of cortisone were discussed.
That is; Ginseng supposed to accelerate the metabolism of glucose from absorption, glycogenesis, glyco¡þlysis to the utilization by tissue cells, and seemed to suppress glyconeogenesis.
Therefore author expect ginseng could control the diabetes resulted from the malutilization of glucose in tissue cells or overwhelming of glyconeogenesis
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